<b>INTERLEUKIN-1β INDUCES NITRIC OXIDE SYNTHASE BY HAMSTER PANCREAS β CELL LINE </b><b>(HIT-T15) </b>
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چکیده
منابع مشابه
Urea inhibits inducible nitric oxide synthase in macrophage cell line.
Macrophage dysfunction is considered an important contributory factor for increased propensity of infections in uremia. Because nitric oxide (NO) is believed to be an effector molecule of macrophage cytotoxicity, we propose that the dysfunction may be related to impaired NO synthesis. To verify this hypothesis, we evaluated macrophage NO synthesis in the presence of urea, a compound that accumu...
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Nitric oxide (NO) is produced by NO synthase (NOS) isoforms: neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible NOS (iNOS). It is believed that, while nNOS and eNOS are effective in regulation of normal physiological processes, iNOS is expressed at an increasing rate especially in inflammatory process. The aim of this study was to determine the presence of iNOS immunoreactivity (iNOS-IR)...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1993
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.14.117